I was working in a lab that had skeletal remains, many of which were Native American ancestral remains. I was used to working with skeletons, cataloguing and measuring bones and whatnot, and had never experienced anything that felt supernatural. This lab was created to repatriate the Native American remains that had been excavated locally and been severely mishandled by the university for decades.
I had a box that contained only a skull, and when I opened the box, I *felt* anger resonating from this skull. The entire time it was out of the box, it was like someone was screaming inside my head. I finished as quickly as I could and returned the skull to its place. I had nightmares for several nights and eventually told the professor in charge about it. She was a descendant of the tribe to which these remains belonged and took me very seriously. She added extra offerings to the altar in the lab and smudged the place (burned white sage) and the nightmares stopped.
Never before nor after have I had such a visceral experience.